Program
| Time |
Event |
|
|
13:30 - 14:00
|
Welcome and conference aims - Ralf Everaers, Sarah Harris And Cedric Vaillant |
|
|
14:00 - 15:45
|
Genomics beyond sequencing – the need for Physical Genomics |
|
| 14:00 - 15:00 |
› Differential spatial and structural organization of the X chromosome underlies dosage compensation in C. elegans + Does the physical organisation of the genome within the nucleus matter : the big picture - Peter Meister, Cell Fate and Nuclear Organization, Institute of Cell Biology, University of Bern |
|
| 15:00 - 15:45 |
› What Hi-C can and cannot tell us about functional genomic architecture. - Thomas Sexton, Institut de Génétique et de Biologie Moléculaire et Cellulaire |
|
|
15:45 - 16:15
|
Coffee break |
|
|
16:15 - 18:15
|
Genomics beyond sequencing – the need for Physical Genomics |
|
| 16:15 - 17:00 |
› Topological aspects of chromosome folding - Angelo Rosa, Scuola Internazionale Superiore di Studi Avanzati / International School for Advanced Studies |
|
| 17:00 - 17:45 |
› The large-scale hierarchical features of chromatin spatial organization - Mario Nicodemi, Dipartimento di Fisica, Universita' di Napoli "Federico II" |
|
| 17:45 - 18:15 |
› Exploring long-range contacts between topological domains (TADs) in ES cells and neurons - Dorothee Kraemer, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine |
|
|
18:15 - 19:15
|
Discussion session - Whole group |
|
| Time |
Event |
|
|
09:00 - 09:45
|
The need for Physical Genomics – continued |
|
| 09:00 - 09:45 |
› Loop extrusion as a mechanism of chromosome condensation - Leonid Mirny, Massachusetts Institute of Technology |
|
|
09:45 - 10:15
|
Coffee break |
|
|
10:15 - 12:30
|
The need for Physical Genomics – continued |
|
| 10:15 - 11:00 |
› Chromatin Hydrodynamics - Yitzhak Rabin, Department of Physics, Bar-Ilan University |
|
| 11:00 - 11:45 |
› Differential chromosome conformations and dynamics in living cells - Kerstin Bystricky, University of Toulouse |
|
| 11:45 - 12:30 |
› Diversity of chromosome organization in microorganisms - Romain Koszul, Regulation spatiale des genomes, Departement Genomes et Genetique |
|
|
12:30 - 14:00
|
Lunch |
|
|
14:00 - 15:30
|
Restraint-based modeling of the 3d folding |
|
| 14:00 - 14:45 |
› The 3D colors of chromatin - Julien Mozziconacci, UPMC |
|
| 14:45 - 15:30 |
› Timing in the nucleus: replication domains and graph theory - Benjamin Audit, Laboratoire de Physique de l'ENS Lyon |
|
|
15:30 - 16:00
|
Coffee break |
|
|
16:00 - 17:30
|
Restraint-based modeling of the 3d folding |
|
| 16:00 - 16:45 |
› Determining 3D structures of whole, individual genomes using single-cell Hi-C - Tim Stevens, MRC Laboratory of Molecular Biology |
|
| 16:45 - 17:30 |
› Colocalization of coregulated genes: A steered molecular dynamics study of Human Chromosome 19 - Marco Di Stefano, Scuola Internazionale Superiore di Studi Avanzati / International School for Advanced Studies |
|
|
17:30 - 18:00
|
Poster Pitches - 1 slide/2 mins per poster |
|
|
18:00 - 19:00
|
Poster session - with nibbles and drinks |
|
| Time |
Event |
|
|
09:00 - 09:45
|
Supercoiling, DNA, Chromatin |
|
| 09:00 - 09:45 |
› DNA Looping Across Length Scales: Computational Modeling and its Application to Cre Site-specific Recombination - Stephen Levene, University of Texas at Dallas [Richardson] |
|
|
09:45 - 10:15
|
Coffee break |
|
|
10:15 - 12:15
|
Supercoiling, DNA, Chromatin |
|
| 10:15 - 11:00 |
› Possible role of DNA supercoiling in formation of topological domains - Andrzej Stasiak, Center for Integrative Genomics - Institute of Bioinformatics, Génopode |
|
| 11:00 - 11:30 |
› Transcription and supercoiling : torsion-mediated interaction between adjacent genes - Sam Meyer, INSA Lyon |
|
| 11:30 - 12:15 |
› Modeling effects of nucleosome positioning in short and long chromatin fibers - Gero Wedemann, University of Applied Sciences Stralsund |
|
|
12:15 - 14:00
|
Lunch |
|
|
14:00 - 16:15
|
Supercoiling, DNA, Chromatin |
|
| 14:00 - 14:45 |
› Chromatin dynamics studied by molecular dynamics simulations and single-molecule FRET - Jörg Langowski, Dept. Biophysics of Macromolecules, German Cancer Research Center |
|
| 14:45 - 15:30 |
› DNA segregation in E. coli: the role of chromosome structuring - Ivan Junier, Laboratoire Adaptation et Pathogénie des Microorganismes |
|
|
15:30 - 16:00
|
Coffee break |
|
|
16:00 - 17:00
|
Discussion |
|
|
17:00 - 18:15
|
Poster session - with nibbles and drinks |
|
|
