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Monday, June 22, 2015
| Time | Event | |
| 13:30 - 14:00 | Welcome and conference aims - Ralf Everaers, Sarah Harris And Cedric Vaillant | |
| 14:00 - 15:45 | Genomics beyond sequencing – the need for Physical Genomics | |
| 14:00 - 15:00 | › Differential spatial and structural organization of the X chromosome underlies dosage compensation in C. elegans + Does the physical organisation of the genome within the nucleus matter : the big picture - Peter Meister, Cell Fate and Nuclear Organization, Institute of Cell Biology, University of Bern | |
| 15:00 - 15:45 | › What Hi-C can and cannot tell us about functional genomic architecture. - Thomas Sexton, Institut de Génétique et de Biologie Moléculaire et Cellulaire | |
| 15:45 - 16:15 | Coffee break | |
| 16:15 - 18:15 | Genomics beyond sequencing – the need for Physical Genomics | |
| 16:15 - 17:00 | › Topological aspects of chromosome folding - Angelo Rosa, Scuola Internazionale Superiore di Studi Avanzati / International School for Advanced Studies | |
| 17:00 - 17:45 | › The large-scale hierarchical features of chromatin spatial organization - Mario Nicodemi, Dipartimento di Fisica, Universita' di Napoli "Federico II" | |
| 17:45 - 18:15 | › Exploring long-range contacts between topological domains (TADs) in ES cells and neurons - Dorothee Kraemer, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine | |
| 18:15 - 19:15 | Discussion session - Whole group |
Tuesday, June 23, 2015
| Time | Event | |
| 09:00 - 09:45 | The need for Physical Genomics – continued | |
| 09:00 - 09:45 | › Loop extrusion as a mechanism of chromosome condensation - Leonid Mirny, Massachusetts Institute of Technology | |
| 09:45 - 10:15 | Coffee break | |
| 10:15 - 12:30 | The need for Physical Genomics – continued | |
| 10:15 - 11:00 | › Chromatin Hydrodynamics - Yitzhak Rabin, Department of Physics, Bar-Ilan University | |
| 11:00 - 11:45 | › Differential chromosome conformations and dynamics in living cells - Kerstin Bystricky, University of Toulouse | |
| 11:45 - 12:30 | › Diversity of chromosome organization in microorganisms - Romain Koszul, Regulation spatiale des genomes, Departement Genomes et Genetique | |
| 12:30 - 14:00 | Lunch | |
| 14:00 - 15:30 | Restraint-based modeling of the 3d folding | |
| 14:00 - 14:45 | › The 3D colors of chromatin - Julien Mozziconacci, UPMC | |
| 14:45 - 15:30 | › Timing in the nucleus: replication domains and graph theory - Benjamin Audit, Laboratoire de Physique de l'ENS Lyon | |
| 15:30 - 16:00 | Coffee break | |
| 16:00 - 17:30 | Restraint-based modeling of the 3d folding | |
| 16:00 - 16:45 | › Determining 3D structures of whole, individual genomes using single-cell Hi-C - Tim Stevens, MRC Laboratory of Molecular Biology | |
| 16:45 - 17:30 | › Colocalization of coregulated genes: A steered molecular dynamics study of Human Chromosome 19 - Marco Di Stefano, Scuola Internazionale Superiore di Studi Avanzati / International School for Advanced Studies | |
| 17:30 - 18:00 | Poster Pitches - 1 slide/2 mins per poster | |
| 18:00 - 19:00 | Poster session - with nibbles and drinks |
Wednesday, June 24, 2015
| Time | Event | |
| 09:00 - 09:45 | The specific sequence- and epigenetic state-dependent folding of chromosomes | |
| 09:00 - 09:45 | › Nucleosome-positioning & Long-range contacts at Topological boundaries - Olivier Cuvier, Laboratoire de biologie moléculaire eucaryote du CNRS | |
| 09:45 - 10:15 | Coffee break | |
| 10:15 - 12:15 | The specific sequence- and epigenetic state-dependent folding of chromosomes | |
| 10:15 - 11:00 | › Structural organization of human replication timing domains - alain arneodo, Laboratoire de Physique de l'ENS Lyon | |
| 11:00 - 11:30 | › The Chromosome as a topological device for conversion of energy into information - Georgi Muskhelishvili, School of Engineering and Science [Bremen] | |
| 11:30 - 12:00 | › Topologically associating domain boundaries serve as hitchhiking platforms for the Drosophila dosage compensation complex - Fidel Ramirez, The Max Planck Institute of Immunobiology and Epigenetics | |
| 12:00 - 14:00 | Lunch | |
| 14:00 - 15:15 | Epigenetic regulation of chromosome folding | |
| 14:00 - 14:45 | › Epigenomics in 4D: modeling the dynamic coupling between epigenome and chromatin organization - Daniel Jost, Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble | |
| 14:45 - 15:15 | › Epigenetics switches chromosomes from polymer to copolymer physics - Jean-Marc Victor, Université Pierre et Marie Curie - Paris 6 | |
| 15:15 - 16:15 | Discussion session - Small groups - 10 groups of 5 participants. | |
| 16:15 - 16:45 | Coffee break | |
| 16:45 - 18:45 | Feedback from small group discussion - A representative from each small group gives a 10min talk summarising the discussion | |
| 19:30 - 23:00 | Social dinner |
Thursday, June 25, 2015
| Time | Event | |
| 09:00 - 09:45 | Supercoiling, DNA, Chromatin | |
| 09:00 - 09:45 | › DNA Looping Across Length Scales: Computational Modeling and its Application to Cre Site-specific Recombination - Stephen Levene, University of Texas at Dallas [Richardson] | |
| 09:45 - 10:15 | Coffee break | |
| 10:15 - 12:15 | Supercoiling, DNA, Chromatin | |
| 10:15 - 11:00 | › Possible role of DNA supercoiling in formation of topological domains - Andrzej Stasiak, Center for Integrative Genomics - Institute of Bioinformatics, Génopode | |
| 11:00 - 11:30 | › Transcription and supercoiling : torsion-mediated interaction between adjacent genes - Sam Meyer, INSA Lyon | |
| 11:30 - 12:15 | › Modeling effects of nucleosome positioning in short and long chromatin fibers - Gero Wedemann, University of Applied Sciences Stralsund | |
| 12:15 - 14:00 | Lunch | |
| 14:00 - 16:15 | Supercoiling, DNA, Chromatin | |
| 14:00 - 14:45 | › Chromatin dynamics studied by molecular dynamics simulations and single-molecule FRET - Jörg Langowski, Dept. Biophysics of Macromolecules, German Cancer Research Center | |
| 14:45 - 15:30 | › DNA segregation in E. coli: the role of chromosome structuring - Ivan Junier, Laboratoire Adaptation et Pathogénie des Microorganismes | |
| 15:30 - 16:00 | Coffee break | |
| 16:00 - 17:00 | Discussion | |
| 17:00 - 18:15 | Poster session - with nibbles and drinks |
Friday, June 26, 2015
| Time | Event | |
| 09:00 - 09:45 | Multiscale DNA modelling - from QM to coarse grained simulations | |
| 09:00 - 09:45 | › The Sequence-Dependent Statistical Mechanics of DNA - John Maddocks, Ecole Polytechnique Fédérale de Lausanne | |
| 09:45 - 10:15 | Coffee break | |
| 10:15 - 11:30 | Multiscale DNA modelling - from QM to coarse grained simulations | |
| 10:15 - 10:45 | › Simulating the interaction of sequence and writhing in nucleic acids - Christian Matek, University of Oxford (UK) | |
| 10:45 - 11:30 | › DNA and its environment: a close look at ion binding - Richard Lavery, Bases Moléculaires et Structurales des Systèmes Infectieux | |
| 11:30 - 13:00 | Summary and close |
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